G2C::Behaviour

SAP102 knock-out mouse

S.G.N. Grant and the G2C Consortium

Corresponding email: Seth.Grant@ed.ac.uk  

 

Overview: Effect sizes (Cohen d) for 16 behaviour variables

Mutant mice showed medium overall behavioural difference from wildtypes, with five of 16 behaviour variables significantly impacted by this mutation. In the elevated plus maze task, two behavioural variables of five were significantly impacted in mutants. In the open field/novel object exploration task, one behavioural variable, OF NOE total distance, was significantly decreased in mutants. In the rotarod task, two behavioural variables of three were significantly impacted in mutants. Fear learning, contextual memory and cued memory tasks were unaffected. Definitions of variables may be found below.

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The G2CMine data warehouse provides cohort summaries and individual mouse observations from the SAP102 knock-out line phenotyping.

 

Variables shown are: EPM total distance, Total distance (cm) travelled in any arm or central zone of the EPM. EPM max speed, Maximum speed (cm/s) travelled in any arm or central zone of the EPM. EPM % time in open, Percentage of time in the open or closed arms of the EPM spent in open arms. EPM time in centre, Total time (s) spent in the central zone of the EPM. EPM max speed, open vs closed, Difference between the maximum speed (cm/s) observed in the open arms and the closed arms of the EPM. OF, NOE total distance, Total distance travelled (log₁₀ cm) during initial exposure to the open field and in presence of the novel object. NOE vs OF distance travelled, Difference in distance travelled (cm) in presence of the novel object and during initial exposure to open field. RR naive fall time, Fall time on accelerating rotarod (log₁₀ s), naive performance in session 1. RR learning, Learning on rotarod, measured as increase in fall time per trial (s/trial) in session 1. RR memory, Memory on rotarod, measured as excess fall time at middle of session 2 relative to middle of session 1. Fear learning, trial effect, Fear learning, measured as extra % time freezing before third trial compared to % time freezing before first trial. Fear learning, tone effect, Fear learning, measured as increase in % time freezing due to third tone compared to increase in % time freezing due to first tone. Contextual memory, mean, Contextual memory, measured as difference in % time freezing during first 120 s re-exposure to the box compared to first 120 s in the box on previous day. Contextual memory, change, Contextual memory, measured as increase in % time spent freezing from first time bin of 30 s to fourth bin of 30 s during 120 s re-exposure to the box. Cued memory, mean, Cued memory, measured as increase in % time spent freezing during 120 s of tone re-exposure compared to increase in % time spent freezing during initial tone on previous day. Cued memory, change, Cued memory, measured as increase in % time spent freezing from first time bin of 30 s to fourth bin of 30 s during 120 s re-exposure to the tone.

 

Variable Units Wildtype M (n=10) Wildtype F (n=0) Mutant M (n=14) Mutant F (n=0) P(sex×mutation) P(mutation)
EPM total distance cm 1208 (123) - 932 (60) - - 0.038 *
EPM max speed cm/s 26 (1) - 22.1 (0.9) - - 0.0098 **
EPM % time in open % 7.3 (1.9) - 12.2 (4.1) - - 0.35
EPM time in centre s 52.8 (5) - 50.6 (7.8) - - 0.83
EPM max speed, open vs closed cm/s -10.6 (2.9) - -8.6 (3.1) - - 0.65
OF, NOE total distance log10 cm 3.7 (0.04) - 3.54 (0.02) - - 0.0014 **
NOE vs OF distance travelled cm -1300 (270) - -800 (110) - - 0.068
RR naive fall time log10 s 1.6 (0.1) - 1.1 (0.1) - - 0.011 *
RR learning s/trial 5.5 (1.2) - 2.5 (0.7) - - 0.029 *
RR memory s 18.1 (5.6) - 11 (3) - - 0.24
Fear learning, trial effect % freezing 43 (9) - 38.5 (4.1) - - 0.61
Fear learning, tone effect % freezing 5.7 (5.1) - 0.1 (5.8) - - 0.5
Contextual memory, mean % freezing 43.9 (7.5) - 41.8 (4.2) - - 0.79
Contextual memory, change % freezing 13.3 (10.9) - 5.6 (8.5) - - 0.58
Cued memory, mean % freezing -3.6 (5.2) - -2.7 (6.5) - - 0.92
Cued memory, change % freezing -2.1 (5.2) - -1.2 (5.8) - - 0.91

 

Elevated Plus Maze Performance

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Variables shown are: EPM total distance, Total distance (cm) travelled in any arm or central zone of the EPM. EPM max speed, Maximum speed (cm/s) travelled in any arm or central zone of the EPM. EPM % time in open, Percentage of time in the open or closed arms of the EPM spent in open arms. EPM time in centre, Total time (s) spent in the central zone of the EPM. EPM max speed, open vs closed, Difference between the maximum speed (cm/s) observed in the open arms and the closed arms of the EPM.

 

Variable Units Wildtype M (n=10) Wildtype F (n=0) Mutant M (n=14) Mutant F (n=0) P(sex×mutation) P(mutation)
EPM total distance cm 1208 (123) - 932 (60) - - 0.038 *
EPM max speed cm/s 26 (1) - 22.1 (0.9) - - 0.0098 **
EPM % time in open % 7.3 (1.9) - 12.2 (4.1) - - 0.35
EPM time in centre s 52.8 (5) - 50.6 (7.8) - - 0.83
EPM max speed, open vs closed cm/s -10.6 (2.9) - -8.6 (3.1) - - 0.65

 

Open Field and Novel Object Exploration Performance

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Variables shown are: OF, NOE total distance, Total distance travelled (log₁₀ cm) during initial exposure to the open field and in presence of the novel object. NOE vs OF distance travelled, Difference in distance travelled (cm) in presence of the novel object and during initial exposure to open field.

 

Variable Units Wildtype M (n=10) Wildtype F (n=0) Mutant M (n=14) Mutant F (n=0) P(sex×mutation) P(mutation)
OF, NOE total distance log10 cm 3.7 (0.04) - 3.54 (0.02) - - 0.0014 **
NOE vs OF distance travelled cm -1300 (270) - -800 (110) - - 0.068

 

Rotarod Performance

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Variables shown are: RR naive fall time, Fall time on accelerating rotarod (log₁₀ s), naive performance in session 1. RR learning, Learning on rotarod, measured as increase in fall time per trial (s/trial) in session 1. RR memory, Memory on rotarod, measured as excess fall time at middle of session 2 relative to middle of session 1.

 

Variable Units Wildtype M (n=10) Wildtype F (n=0) Mutant M (n=14) Mutant F (n=0) P(sex×mutation) P(mutation)
RR naive fall time log10 s 1.6 (0.1) - 1.1 (0.1) - - 0.011 *
RR learning s/trial 5.5 (1.2) - 2.5 (0.7) - - 0.029 *
RR memory s 18.1 (5.6) - 11 (3) - - 0.24

 

Fear Conditioning Performance

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Variables shown are: Fear learning, trial effect, Fear learning, measured as extra % time freezing before third trial compared to % time freezing before first trial. Fear learning, tone effect, Fear learning, measured as increase in % time freezing due to third tone compared to increase in % time freezing due to first tone. Contextual memory, mean, Contextual memory, measured as difference in % time freezing during first 120 s re-exposure to the box compared to first 120 s in the box on previous day. Contextual memory, change, Contextual memory, measured as increase in % time spent freezing from first time bin of 30 s to fourth bin of 30 s during 120 s re-exposure to the box. Cued memory, mean, Cued memory, measured as increase in % time spent freezing during 120 s of tone re-exposure compared to increase in % time spent freezing during initial tone on previous day. Cued memory, change, Cued memory, measured as increase in % time spent freezing from first time bin of 30 s to fourth bin of 30 s during 120 s re-exposure to the tone.

 

Variable Units Wildtype M (n=10) Wildtype F (n=0) Mutant M (n=14) Mutant F (n=0) P(sex×mutation) P(mutation)
Fear learning, trial effect % freezing 43 (9) - 38.5 (4.1) - - 0.61
Fear learning, tone effect % freezing 5.7 (5.1) - 0.1 (5.8) - - 0.5
Contextual memory, mean % freezing 43.9 (7.5) - 41.8 (4.2) - - 0.79
Contextual memory, change % freezing 13.3 (10.9) - 5.6 (8.5) - - 0.58
Cued memory, mean % freezing -3.6 (5.2) - -2.7 (6.5) - - 0.92
Cued memory, change % freezing -2.1 (5.2) - -1.2 (5.8) - - 0.91

Acquired (raw) data

Animals tested in the G2C behavioural phenotyping battery

Cohorts are summarised by genotype and sex, followed by a list of all the animals from the line tested. Shown are the unique radio frequency tag id (RFID), Genotype, Sex, mouse batch identifier (Batch ID), date of birth (D.O.B.) and data of RFID chipping (D.O.C.) for each mouse.

View experimental protocols.

 

Behaviour Cohort Summary

GenotypeMaleFemale
+/+100
-/-013
-/Y140

 

Individual Mice

RFIDGenotypeSexBatch IDD.O.B.D.O.C.
089057295+/+MBATCH_07-0909/01/200725/05/2007
089617013+/+MBATCH_07-0909/01/200725/05/2007
089113534+/+MBATCH_07-1227/02/200716/06/2007
089349882+/+MBATCH_07-1227/02/200716/06/2007
089362271+/+MBATCH_07-1227/02/200716/06/2007
089770117+/+MBATCH_07-1227/02/200716/06/2007
092121327+/+MBATCH_07-1229/11/200616/06/2007
092323775+/+MBATCH_07-1227/11/200616/06/2007
092627541+/+MBATCH_07-1229/11/200616/06/2007
089109582+/+MBATCH_08-2220/05/200824/06/2008
016003039-/-FBATCH_09-0211/09/200808/01/2009
016009127-/-FBATCH_09-0213/08/200808/01/2009
016011103-/-FBATCH_09-0220/08/200808/01/2009
016014299-/-FBATCH_09-0213/08/200808/01/2009
016032122-/-FBATCH_09-0220/08/200808/01/2009
016034006-/-FBATCH_09-0220/08/200808/01/2009
016556583-/-FBATCH_09-0220/08/200808/01/2009
016558381-/-FBATCH_09-0211/09/200808/01/2009
016559843-/-FBATCH_09-0220/08/200808/01/2009
016564886-/-FBATCH_09-0211/09/200808/01/2009
016579531-/-FBATCH_09-0211/09/200808/01/2009
016581599-/-FBATCH_09-0211/09/200808/01/2009
016583104-/-FBATCH_09-0211/09/200808/01/2009
089082076-/YMBATCH_07-0904/02/200725/05/2007
089356568-/YMBATCH_07-0902/02/200725/05/2007
089379854-/YMBATCH_07-0918/01/200725/05/2007
089585861-/YMBATCH_07-0909/01/200725/05/2007
089043619-/YMBATCH_07-1214/12/200616/06/2007
089339819-/YMBATCH_07-1227/11/200616/06/2007
089550774-/YMBATCH_07-1231/07/200616/06/2007
089632351-/YMBATCH_07-1227/02/200716/06/2007
092321084-/YMBATCH_07-1229/11/200616/06/2007
092321620-/YMBATCH_07-1209/01/200716/06/2007
092631061-/YMBATCH_07-1208/10/200616/06/2007
089052349-/YMBATCH_08-1104/12/200717/04/2008
089079607-/YMBATCH_08-1128/12/200717/04/2008
089307857-/YMBATCH_08-1128/12/200717/04/2008

Elevated Plus Maze

File NameSizeChecksum (SHA256)
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089550774.mpg10749952514000516affd8b3ff2f126da66eb8eca833a076cfc1b4be7abc48f52e0abd8e
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016564886.mpg9953280cc1a7c56f10f5517a50de810ad36935bdc856a0952ff87c8a5127d0de427066a
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016011103.mpg9852928ba0d5ffa68e5c312fcd89c23de267f5b2a34967f467392b1abc5edf05e295f0a
092323775.mpg10067968e6122e49cb5f7554d457c28ab80344d57814bc1b0acc7ddca8dc4b71da772e52
089339819.mpg10416128021722d5c3e47c84a8023bc7250a21fdaebd192909cea2dd3d69a83adb49db46
089349882.mpg10008576b60efd174eef5367525992962c565f5da39e31fd97bac554d7f8b59c5a1fcc23
089109582.mpg1037926401da44a6048ea0f5431b2ad985b4dd0852613f5757d11b5d82007f097c67145e
016556583.mpg10573824de4e9a299f6c4dc28a14e1d41ba382e76367dcf0d7bb931912b495bcd53d3b34
092321084.mpg978739201d5f44b66fbfc4615edc93bc6a6a4cee1f95331958f1ac828b7609763385851
016581599.mpg9582592d6112bca43daec0f5da8fb0ef7bcc6e250044348d3505e620481520ad52cf5a6
089339584.mpg9910272ec52daf23405ecf5743430793a0eff2cd99bbd4d073dea3130a750f83e987f57
089356568.mpg9979904e570aae4dbfa207016f80d765f374c46cc044829090b890aaeeb1f5bb4fd03ea
016034006.mpg9943040a654a56977d80d4104c789634944b931e03062390d8f4cde3f6c526c51b1c095
092627541.mpg9893888cb1850d2faaf4a6b169ea9f00be1f7c4cdfe2cc6d4f56bb7d2e16c2291e0d40a
089632351.mpg10436608899ae2d53fe57e89b89b4f566c521e69b0e69879006407c75546f664d7d10fdb
016003039.mpg991641642bcbef52127ac4507809b32a47eef6e3648aaf53c1f0bfb4ecb026425c83ef4
092621310.mpg101888004ebb3d4b089cd4bbcff19ea226f734ab2a5ee69547b57fd6556f22facc61220f
089585861.mpg10203136ec65c5e0f400e6b7d91468f4cc621d4982097f668efe6f692a2e24e58107b8a9

Open Field

File NameSizeChecksum (SHA256)
089362271.mpg13049856aa221a6206a49026426bc1573b6ad2910ec3b428f46c7d200733c2d13e71d37a
092627541.mpg12906496dd5f05f7447efdd52343959cf542f8020f1b39ed9f1ed0bf51db4a3cd3b825ed
089585861.mpg8675328e50171e98519605774275c531c044308ee80a19c7a1444d5a227467f80948470
016017844.mpg10559488caecdd06dde66ee7e4f8c8090712eaa57f9548daee9ff8d809118eec2107759f
092321084.mpg12937216f368feeacffc9f51dc4577285cf1a2f57c8a56b2809d4abbb9938ae8d68ccfd4
016014299.mpg1140121612a8d817dd8fc00c821a964e463e2a489b4ccdb8732387c1239940f7eeca46b3
089113534.mpg130785281764930be56d3246524ffb9e091f06cdd7e4632470d5bf652bac2e8200b3d979
092321620.mpg132546568cacb598b08c324e1467719bab435345e85b63f311c24709220d027c4270a431
089339584.mpg876953646d355fa4cfbee3bc28f582020b01873aa26c6891a76c7d217225341214da533
089057295.mpg87367688f966d0da5a9a2e00d9cd04de46675354358a1fc549137114e09e0606a5f98aa
089617013.mpg10307584bc719430a227f0e3b7dfce8745021afbe281fbd9f0786c99e3b4a4a32388ea5f
089550774.mpg12982272721d92c87831edc622df246a955a50dae66a3da2e934cf1d331ab1dc7e043c62
089082076.mpg103075849df31f25beb46f1cc3b563fd81e0f966dd3097971d2da1b557d58b7b097f6231
089342049.mpg129556482f81468971ef0c9bec7d45ca69b76b124b36797ddd18cae1e50886b547ff7338
016003039.mpg8458240f8f09bed377421f697e3c06a28c3cbd37a00d6b04ada48e548b30388a2953481
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016009127.mpg913408076d5c216bccaa255b2558662e668f653189bc41bbefd05d40c620c432bf88ef1
092631061.mpg12931072ea8848594e97d2d7a0734c999b494c9d83d930f6200f1cb832c76e22e96fc2c0
016558381.mpg8519680206041cf13a9a70fc619a36e30eaa6faec7ef2504c63a6d4f288452c5e7a05e7
089379854.mpg10379264da853f0cc2e9c41bf8d39ccd83cbb2e14d3d89d37cc0108c11269bac9c559b4d
089307857.mpg9103360dd56ee89bca39bbfe2a608dce236da24ba10f2c945662413898e1529d8017d8e
089349882.mpg13543424faad923ce236b1c5cdcf230eafa07d64243a77df5eba0a28ecdcd4a9f8d82db6
016556583.mpg10321920f6435077bdf4ae05ce5678919bf4910d88f6ef23179fc892c30f2aee5dd37b5c
092121327.mpg12969984260c1ae90ad9d2fd221f5064e314a0227d83de9551661383be0ca5530cae9989
089088617.mpg1308262424ff15b7fae3f72fd9dd5b515f073e13f9c251a1f5820b2dbada79e5181c291a
089356568.mpg1039974439c96b19da339a329ec87e9b41faf751c3ed7dd4316c824dd11e60851b4eb3c1
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089052349.mpg105226241c134fda9d1cecf43c1c6e2767eb703e5226a4ffd3e66ee7ceff6bc8f1c2dc96
016583104.mpg843571250bc07ba8a23b8343833cb98a12ab17802747ddff269048ba3289a77255f3029
016581599.mpg10647552a844490197d20772d3d5f0e9b6ad6ef369186581ab7b2d336562aeb2054b70e5
089536882.mpg13225984e07e0ef48fd655bd52be0e20790d71ecbd53c6870aaccc48f368f075eb8cfd33
016011103.mpg8681472c12e9628336824453f93689901165846f2f1d4fb82f323e40754bd9c564891e2
089770117.mpg13058048d5404a3da935300b0e108b65e741562ef32750243d39887083a8f7da3e5e755e
016559843.mpg8374272132fdc9c676d42313978b71a3492a7c50695418f236068046bab4e077593281a

Novel Object Exploration

File NameSizeChecksum (SHA256)
016014299.mpg10543104057af989fb6f8361d2536de9c042f2f12da4a7f4305aee0fe3d77286347741c1
089113534.mpg12963840cff9183473684a6ee62b10ae60ba3a6ad1589e5d3f6ced8293b2d78b01009d7e
016011103.mpg8646656d9b00a4bb8043cc47e1e8300dd6ae08c4da111ea6e37812babe1296a960008c0
089617013.mpg10665984391cba4542521d89cd7bcb630268127663c5aafce217b33838d454e45da8aab3
092321620.mpg12963840acb1bc8fd75d124d188385a899c659a6843efedde641abdc787755839434c127
089585861.mpg88739840fde0a320583c75565356542f7cec191a60faf167cbe5977e57fa813c9b770dd
089362271.mpg12994560f4d9a1a1af79739871b27814fd46bb5c8ae5e3e4db985e227a09d24fc5b59e79
089339819.mpg12935168ad8c97bcc2b6bbf6a96e15f4f649ee6f7f4d6c863ca8da239e7a2b957c8692fb
089088617.mpg1238220835d0ad9bef28818548071fadf4524f8bb2c997cc03f0d1c72a47c284b787746e
089079607.mpg11055104d8212a478833f86ac093b72ea749cf13885b3771c59fb9d90f89e0296e2d07bf
016009127.mpg85770242dbceee4ff5636fedffe148b23114f28d157330ca1869f4b7112a75a05b66a06
092121327.mpg122019849fd624268f04413e3ed6a2ab54eac8c10876255f8c31872e722829fb4255dc0b
089052349.mpg109199362ec1c3602252409bcacadc477a899c05adc1a6fcb014f0f0882d8eae1479b4ee
092319528.mpg1350041654e96ff36b68cd10a8413a78701161a6d01ced4239349841b103fe8371a6add3
016003039.mpg86241280e46731a06fc5b28f2f011f027ac967084eda95bd08dc091db890de243703352
089043619.mpg1347584025d71eccc2c8e7786cc2645a7ad4f556d93f7916ad681ada4502486eeff2d250
016032122.mpg8869888e1f50a03c82efaf79d0c4e7b4f0dda151c341910abd794526b669d78473340e1
089339584.mpg8873984f200fb3bbdd0dff1348a65c7c6c0627234ceb32b9a9a0c8432159d9b8233e551
092631061.mpg1229824001c00aca4969a8096bc74d6ab6a28b98979cff9e177f3979ddd76c581a93fca6
016034006.mpg109527046b5880dbb3017465327c6d433a0624e353400710391cc6f769d63a14e76c5967
016564886.mpg10727424e4695ae5560aa02d4b1c626750b450e5a629f14a470c9996239ea398ef5f826d
089048795.mpg8878080c02804e0ca156e94373a14b76b7816b36cf5980f14b8899f22d651c58d29c665
016583104.mpg86855688a87cbaec83daa12cb2de1aa8bed93d79034e948ed281b50220414b3a36747c9
089307857.mpg9308160b8c0e7e3b9493106efe17d2a63595f51083c4c9c08556c3cc0823e320ebf9365
016581599.mpg10917888d4af9f516e2d65b8c7c4779377e93101c640a369efe94a1cd235527b78f7a484
089342049.mpg130252807847f76d92e25ef04457ea6cf4f5ae301944e09d029832351659e651077d6df6
089349882.mpg1292697636adafd24c8defd357bc9a5f362bb07fd3d56ca8f4d31cb1b64b23987117f3a4
016579531.mpg106536962c36992f082ec1940c2aea9084668e1a8ffce5942949aafcb43e8ca0ebd95669
089098284.mpg91238400fbe2d5258c738ef90d1dcc893df7e158c775456a333861c5a8653d914304b9c
089082076.mpg108646408263df5f66e78ac0737af6b6f4ed35fbdacb38044d821bb1771864778daae4cb
092321084.mpg129146886e0310d930769348549903d5f08f8f7c2ad51df49173b9d0785be34f18cfbc94
089057295.mpg912179255aeb3e1cfee0ab89789a9820d106261fde53680481f5ffded5bc62cfc4d254a
089536882.mpg129351687d2646c74fdcd914c40c5aa5444a54aff8a9affd4e35df1b5984e490b32310db
016558381.mpg8738816a574f6737622a84c7c9f4cda1b84c31cb44fead7ea096dec8124818bd1f91a04
089109582.mpg86261763667c7cc0882cfe8ab7fbcade314a0e253c0f1781cac045a9a7ebe26d238c302
016017844.mpg10711040847cd42c1fa4180d840395ae6247218d8da769237a2a97d7d77b5e50485c1988
089356568.mpg106680321b7f892fa13ef4ea9ca1919cd768e51eddaff867e7efe4b8e639dcb44b5468ad
089770117.mpg1293926458174608772337c804b754eb9b64c71f41b4b0952a11b21a86a1a0400aed801a
092621310.mpg10786816f0a1ac56be495fb626b98f63d97e450ef129223622b393b83361329933333e82
092323775.mpg12912640848c7186d30c9c6a12f2524f2feb68f52fe69bcb8b0c639c2b8a00f04f2e2b86
089632351.mpg12292096d528875f0338ca7a5550e43755a21b17cf7691b8ca1ec2619413ea6d932f71a5
089379854.mpg106352642c543746d5b6cb476ae786ff5747cac2c1fba102abb3fb4b79f71c1c13ee6c7c
089550774.mpg130457604b3f72643d5eed4dd21f14a36ced46cf9ec0403f29681307513850a42747500d
092627541.mpg129413123f8a15eb312ecf10a58698000824a51ecde252b8e05da2517dad005e84e59304
016559843.mpg8542208816f4304fccd257cba354842d4e9c4d0e2d670682843133febf36f48d35c77d3
016556583.mpg1072537661222de3f93bceea9e6c3eca5c1e1c05b80563a9806236403d9dd081984eaa28

Rotarod

File NameSizeChecksum (SHA256)
089770117.txt491018c11f6f3d3b706f877f000287994dbbc277e6d86aa2f5ef54e4c14aeb9a664
089550774.txt4901a360931850a54aefb716e6fdafd1b8e28a58b11c59db8e40f57ac603cd82ae9
016579531.txt490816804de4c737d079c22ccb04dae4dd9fffdcb005077bc7c28e4b0959ca76f88
089043619.txt491085caf71a9a2e2888d56a1003100354859cc4b4a7200935bb98e1d17cca0f92f
089307857.txt4970f306af131dace35c18d2c3d387608c1e88f83155cc4a96c438cbf390af80866
016556583.txt495b455fd7c0d3d753324b3b6728037431daf232e046042d7e0eca00a6aaaaf9c48
089339819.txt4919d28efb6836ad7e00f8c6fe4f861c13a142c43eb06c2dff23eb01c4a98f35596
089082076.txt496f34b499eb961bddbcd15f2ee05d42cfa58f29dbfcc544c3a10cfaf221e823138
089632351.txt4967b8364f270951a2fb5c09945bf961676081e3b12b3ddfe8df2a4227e8afe82b9
089079607.txt4965124cdc5b5fd28bc82bcfcf2f0cb1eb6517a39e05d0aa29d76d1c674a3c7ec3d
092323775.txt490489d7ca2fd74e81f359e360d4de74960895cb803e0267a88db32b4337e0685af
092627541.txt4908b4be2d3ff1827b7cc4b963dbd449df2b7f87d9681a3b1b291c2e03c30b46ea9
016559843.txt479078daa00e1c75a811908f554a6f800d254073082f25d724880b89da7301b5138
016032122.txt503c394a6ecc0379b536adb274c0ef011d20bb6820b8d57d74d81e533f1f4975aed
016581599.txt492836aa12370fff0fe3d28ea7fb69abdc33e11c5ff7f3e21aaee37a0e0e0c7c155
016003039.txt48732b4cd02cca39294e0a5c4d017fb79efc572bddb0a50cb8e8003698f36a387ad
089585861.txt4938547051886ee61ed01016375df5ea4099fd08aded8907795c2b78ed68209baac
089379854.txt493ef496eb6c21b44b9a458643fe5f81ca6320816fe082a3748b260f95174df69a3
092631061.txt4951494dc54899948542f4431418336de7037dbd6f8923ee4e0540dae57373a9691
089356568.txt4902127123e56e8a141a735f97e90e54547a668d8e44d387e53444d25063fb27762
092321620.txt492be35f5169eaa35c2e3b54de8cce991d90410e65b9cf289d75eaf0247f4dad3bb
089109582.txt499bb10d4723ce289525b543f20a7d9ce73a3b468c9c5ddaeb4770572ac922d5eb7
016014299.txt4939f51470244734f6a6d730d8282d03eae0bc03ccc77dcafe86a206eb92048a392
089052349.txt49645933e76311d9795253ff0a445bc06dba1d49a6e6b217f465b8708f3796fac65
089617013.txt496a9f87d996e2be4fb716eb0d0a9aa85b4af4dbaaa9463badbbe5f1c292582aafd
092321084.txt49314e32916eff805bb003f5fd8f7c5a4cbb83598c53c267d5eb6e87aea1007dfd1
016009127.txt488a1326b8d007d0a03716256cad5fa99c0ca0b45ad1b6b5c639af1309e306ffb6e
092121327.txt50583d38d018a49fd1547a94891ed2f2a2c21b28cf7fde4cdb66b67d6fa8167e92b
089113534.txt491dfcb26a57ea124c770297808b0e61a223828f5526781f2acb37ec49071317462
016564886.txt486ccea2abdf3bd82d2681b09612e1ac764fe875b4f02fa503f263068ab5e948ce0
016558381.txt485d188e7a82107bae91649c8fa279139315e239527590113d35fd7ef474e6704b8
089362271.txt501c762084fea3ed2aabd6098ba1a8ba616d8125c1a6b104688310039970da515a0
089349882.txt501c289961bebae308d89402aee1bda806e6ba7f8b469c0e4a26051908d1af37a8e
089057295.txt502f45bb6359b6dba55a3c4a554d00685c4b933841375060f797fcb20d194272802
016583104.txt487732c28a0ce3412e641f1bf96b73d17c43ffcb220f39e4300b56f4e703649883f
016034006.txt487907723128e4e608c94ee589331a32d7ee4badbd4c54b348700677d0f13c91a70
016011103.txt49158634730d4fe9701d565945d8be8306febccfee5c910e3d362e2ab5ec2d1f7d1

Fear Conditioning

File NameSizeChecksum (SHA256)
089632351.ffii1138946409c2609cfab9b7715a125bd082d075e8cb2a29d88ce148d623c57bf03b0752a1f
089339819.ffii1138946403f21b16d268600207e7c3e361dc183b7a0a8199ed6de7fc6675a1ab14fa39b85
016558381.ffii113894640798eebb2a498171dcfcd5e198a93aae5ff5779efeedec521beb952d6d54af844
089307857.ffii1138946403b453baff1cac434e3ab2c54fe7cf2cc1f7345d10db4a42224659bb21550446d
089113534.ffii113894640ffcaf1b8a091f01147719ecfcdd2be95d3c24fce8629b457a80937694c1da334
092323775.ffii11389464012fcb24641a0d69ed2befc1bcf3837e989f89aaee419052aee093cade9062bd6
016009127.ffii11389464060f0b2edefc9340ad87961ac70416591fd1800f13491885551109349ebfdaa96
092321084.ffii1138946406bbb86035b9210b53d07287a38ab7d1db09363334ed363f5242eb011e57ca447
089043619.ffii113894640185aa0d7b0c9bf357dbb44901c0dd371d9a2b0055f9d66ac33912e800f71c784
089109582.ffii1138946404d7b6c5746b72fba917404a43f38c637c212d738bb675bd207551c7e9502cee8
089550774.ffii113894640d486c0aa1135dbd9e6fe68a6af08fa2ee8186e338a0991aec4aee2150aa7b3b6
016003039.ffii1138946403b955f78cb1fce17b910ec108c48eb287a0b4af8addfe4c686777a5db19ccc18
016014299.ffii11389464037c409f24990e572ad5064310973b2565347063e966155b1dcdcc8e09f18e1d5
092321620.ffii113894640aa91aec0dd7b361a6c0fa18e14e943a57359d1f854996a4e399c2de6571753d3
016583104.ffii113894640173880f96a615a5191b5143ad160a2aa0397ac32ed794b7e97eb45c2011d3c69
016579531.ffii1138946402c27976526adefbf36d7fd3ce3edafa291bccbf422cd36972ed7d0468233cd2a
089349882.ffii113894640af96184c6e233f30b3585a33ff93362b864dbf5de8d13e1b73a978b28d944788
089052349.ffii113894640068df70cce2bac6ad87a015aa160b895d7e38d0300a14fcf0ba26c94524e0af1
089079607.ffii113894640443e17a7140064e16bfff688c6818cca441e16f857f044bf19963b758d5102c8
089362271.ffii1138946400f9c410c30ab59f39d0b5c92d37bdd20ca394a79b7d65a57b44e3518333b3004
016556583.ffii11389464051a70462a24f68ff55aba570716051749e0d8251a5c46008e1e8f6e9ef37d7db
092631061.ffii11389464027ed8e110facddaa3fc0e9c63277a66e1f0a2f9895527898c3f8d720804aea53
089770117.ffii113894640182129d77ccf9f5d1da84456b41f3fb16bf81ee0c0b2805df9bf2011700009cb
016032122.ffii1138946408234dff825c65a0740f80eaf0194d70f652fc3cb8f6a4cecee5743af9231adae
016581599.ffii1138946404abc640b5cc344386ed4bde68e486e019ba8a014b43b7b704ce317bf31255848
092627541.ffii113894640222511596311c238a8b9886c93764ff747b9c496e81d90b25dd938cc91c47096
016034006.ffii113894640810ee90f5c10022c5b9b53da2117afdadca16cf97723afa56599fc56dd20dd49
016564886.ffii11389464026124133df3c82ba5badcec92cff3e24a85a539dc03236e88f75efdd1da9337a
016559843.ffii1138946402220d8c121c0f6ecdd14bbf8775324599ea59cc071825efd63f1d7936250d105
092121327.ffii1138946400c43b91640c47e46f792b979a60fa749e2a2de75b1e87488b0c1726d2a27fb70
016011103.ffii1138946406f26f743b06881d8d820be720eabdb8eaec697c8b31bf61395bf9d6ef74e216e
File NameSizeChecksum (SHA256)
016581599.ffii84082320f5e1174a36b1225c5dc08529912e61e927333d35f8840a1de9a159924d28973f
089585861.ffii84082320c505d47f4c867c573688ddfa7e7e0ca4c38dfcf6aa1daddbd9cb43ff43e08eb5
089632351.ffii84082320eae04750c8dd836863f51063cee4c5c183842a39782c3e7e45dda7966456b0fd
016579531.ffii84082320dc70f60ecbeb78015b54fc68b862abbd58140957f96e3695385d39f29131597d
089079607.ffii84082320179a9266f545ac399e404873f3f7ac3f3f06435c8348197f55ba180709d0755b
016558381.ffii840823205af3e5ae7336d20be6a9fcecfc1a22183001cd593a6f14106d5863cb58a52f5c
089349882.ffii84082320a9f09a68ddc1b430a204c281920d64743ad649beb46471f794eb6c8e78ce5172
089109582.ffii84082320c6494233caf198b4500cf5cf6a46a3d2d7d716cc06375896c0310ddffcc6fcf8
092323775.ffii84082320f78610a069024c00dc5699f9fa7e93eb487913f64c95b66204d00ee24c23e008
089362271.ffii8408232008fd08c9016f9e9cf815836373d92e61c5d4b08660280fa19a8be595c21f252e
016003039.ffii8408232082d7439416440bc0c69acf723b00d89712d8a10bae7ef7332d0db90f615041d2
016559843.ffii84082320ead8ee6c20bd97ded573f4f402583c0c42662bb72fb7d322a19bde2b7cb2a552
089617013.ffii840823209ce9279c8e352376f7807550190e301eef908f9a3b395694cdcfa056ff2c0f68
089057295.ffii84082320e28040b414a951209090b42539c41dc4bf871c2f8539b3be3b648d0a25188609
089307857.ffii84082320da09781202dc340093a3e9dff73efd5bf45515e50b7eab387feffae90a772e0a
016564886.ffii840823208240c0fd22533bc88f4d96b2dd9b6d49a965e69b5c072a7f978e6f94deef535e
089339819.ffii8408232078de20ada256fcfc4537caacadf409224064b0d24a8856509a0621f5bfda3642
089052349.ffii84082320073a8d8f5f23185b587104d3ba64b1c39d81993d0c712bb6341dd7024e4344c2
016011103.ffii84082320620019e4836499ec288aa554e1d9a5c7d522d7e12076d5bfdb0f1597a772723c
089356568.ffii84082320cc547349a17511d1b8009a552fc315df931bf370cd3b46bd1aea01a3cd31d795
016032122.ffii84082320de31bcc5177530ab7eea8e0ac43258a36e71dd194d8f009117d9baafbfd323a5
089082076.ffii8408232034b69836d5e69f9ba9c6058d239fd5f05c160921cbfc7be785354b403a63fec8
016556583.ffii8408232008ba3c0b7795109aad1902591fa3fa54e259579a461994552e482f5d9d2bd2fc
089113534.ffii84082320a216c4a2f25515e8515ae775e4900e826d00424ba0ac47fb4c4fd755963613d0
016014299.ffii84082320a7297612a367caae5c6317c10c5f3f6cd71fb18fafe5f6b9bd2876ce7edf0be0
089770117.ffii84082320ed53c02836b248fb8961229e9452203f735fd9293621d8e54d775ad8db4cd700
092631061.ffii84082320af4470e279e2fa4e0f71a9d2c3e0b07389532e73f586cf97aa162b97f9078a5e
089043619.ffii84082320f16def85a1b548342fafddd4d1b2bce15afa413be0750addd177a270ba9853d4
089550774.ffii84082320da52c23cda01193703bb379012ecbbff39c9172e1632224f257ecc5d1f70da2c
092321620.ffii840823206ae8028d477d4b8d306959c65e78c8163f15d1e2d2c3e8c50a1fd17801d8ba14
089379854.ffii84082320cea72f69d99f1bf6659f5240c926b4f68cc0694e88ef9a1e64871354fef112b6
016009127.ffii8408232029e98ec25beddeb5a2e3850cb5d19ce60108d67382c8167848d7aea48f5ee110
092321084.ffii840823203d4a6f33745e633a3edc01fe42dde5a69465c87fc5d2cd079c35324a2a5848b0
092121327.ffii8408232065f1bc7a43257d4cd34b316633bb84883d247ec0190a0779d86aeff5431cd975
016034006.ffii8408232027319391507ddb1195cbb2ac02002c2b8152fee8588d255b577f53e6097f444b
092627541.ffii84082320ec7754759b91210dfce2d4f9aafdba4c317fb15a8c7e6abfa16034f95101eed2
016583104.ffii84082320bc6cb284422ac8aab42496840d8eaf25541a823729fef5bb534ee131bb4562ba
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EUROSPIN (FP7-HEALTH-241498), SynSys (FP7-HEALTH-242167) and GENCODYS (FP7-HEALTH-241995).

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