G2Cdb::Gene report

Gene id
G00001313
Gene symbol
GRM5 (HGNC)
Species
Homo sapiens
Description
glutamate receptor, metabotropic 5
Orthologue
G00000064 (Mus musculus)

Databases (7)

Gene
ENSG00000168959 (Ensembl human gene)
2915 (Entrez Gene)
96 (G2Cdb plasticity & disease)
GRM5 (GeneCards)
Literature
604102 (OMIM)
Marker Symbol
HGNC:4597 (HGNC)
Protein Sequence
P41594 (UniProt)

Synonyms (3)

  • GPRC1E
  • MGLUR5
  • mGlu5

Diseases (3)

Disease Nervous effect Mutations Found Literature Mutations Type Genetic association?
D00000166: Schizophrenia Y Y (11326300) Microinsertion (MI) Y
D00000166: Schizophrenia Y Y (11326300) Repeat polymorphism (RP) Y
D00000196: Leukodystrophy N Y (14722582) No mutation found (N) N
D00000192: Dystonia parkinsonism (rapid onset) Y Y (15254951) No mutation found (N) N

References

Literature (42)

Pubmed - human_disease

Pubmed - other

Gene lists (8)

Gene List Source Species Name Description Gene count
L00000009 G2C Homo sapiens Human PSD Human orthologues of mouse PSD adapted from Collins et al (2006) 1080
L00000013 G2C Homo sapiens Human mGluR5 Human orthologues of mouse mGluR5 complex adapted from Collins et al (2006) 52
L00000015 G2C Homo sapiens Human NRC Human orthologues of mouse NRC adapted from Collins et al (2006) 186
L00000016 G2C Homo sapiens Human PSP Human orthologues of mouse PSP adapted from Collins et al (2006) 1121
L00000033 G2C Homo sapiens Pocklington H2 Human orthologues of cluster 2 (mouse) from Pocklington et al (2006) 13
L00000061 G2C Homo sapiens BAYES-COLLINS-MOUSE-PSD-CONSENSUS Mouse cortex PSD consensus (ortho) 984
L00000069 G2C Homo sapiens BAYES-COLLINS-HUMAN-PSD-FULL Human cortex biopsy PSD full list 1461
L00000071 G2C Homo sapiens BAYES-COLLINS-MOUSE-PSD-FULL Mouse cortex PSD full list (ortho) 1556
© G2C 2014. The Genes to Cognition Programme received funding from The Wellcome Trust and the EU FP7 Framework Programmes:
EUROSPIN (FP7-HEALTH-241498), SynSys (FP7-HEALTH-242167) and GENCODYS (FP7-HEALTH-241995).

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