Publications - Seth G N Grant

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Synapse proteomics of multiprotein complexes: en route from genes to nervous system diseases.
Hum. Mol. Genet
Dynamic regulation of endoplasmic reticulum in hippocampal neuron dendritic spines.
Eur. J Neurosci
Robust enrichment of phosphorylated species in complex mixtures by sequential protein and peptide metal-affinity chromatography and analysis by tandem mass spectrometry. Science STKE.org.
Proteomic analysis of in vivo phosphorylated synaptic proteins.
J. Biol. Chem.
Analyses of murine Postsynaptic Density-95 identify novel isoforms and potential translational control elements.
Molecular Brain Research
Differential expression of two NMDA receptor interacting proteins, PSD-95 and SynGAP, during mouse development.
Eur. J Neurosci
Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression.
Genes Dev.
Identification of PSD-95 as a regulator of dopamine-mediated synaptic and behavioral plasticity.
Neuron
Proteomics in postgenomic neuroscience: the end of the beginning.
Nat Neurosci
Phosphatidylinositol 3-kinase regulates the induction of long-term potentiation through extracellular signal-related kinase-independent mechanisms.
J Neurosci
Identification of PSD-93 as a substrate for the Src family tyrosine kinase Fyn.
J Biol Chem
Synapse signalling complexes and networks: machines underlying cognition.
Bioessays
Systems biology in neuroscience: bridging genes to cognition.
Curr Opin Neurobiol
Neuropathic sensitization of behavioral reflexes and spinal NMDA receptor/CaM kinase II interactions are disrupted in PSD-95 mutant mice.
Curr Biol
Separable features of visual cortical plasticity revealed by N-methyl-D-aspartate receptor 2A signaling.
Proc Natl Acad Sci USA
Clustering of neuronal potassium channels is independent of their interaction with PSD-95.
J Cell Biol
SynGAP regulates ERK/MAPK signaling, synaptic plasticity, and learning in the complex with postsynaptic density 95 and NMDA receptor.
J Neurosci
Putting tubby on the MAP.
Nat Genet
Isolation of 2000-kDa complexes of N-methyl-D-aspartate receptor and postsynaptic density 95 from mouse brain. J Neurochem
Proteomics of the nervous system.
Trends Neurosci
Proteomics of multiprotein complexes: answering fundamental questions in neuroscience.
Trends Biotechnol
Proteomics in neuroscience: from protein to network.
J Neurosci
Multiprotein complex signaling and the plasticity problem.
Curr Opin Neurobiol
Proteomic analysis of NMDA receptor-adhesion protein signaling complexes.
Nat Neurosci
Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo.
Cell
Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein.
Nature
Mutant Mice and Behaviour: Recommendations concerning genetic background.
Neuron
Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to eag and cyclic nucleotide-gated channels.
Proc Natl Acad Sci U S A
Rescuing impairment of long-term potentiation in fyn-deficient mice by introducing Fyn transgene.
Proc Natl Acad Sci U S A
A role for the Ras signalling pathway in synaptic transmission and long-term memory.
Nature
Analysis of NMDA receptor mediated synaptic plasticity using gene targeting: roles of Fyn and FAK non-receptor tyrosine kinases.
J Physiol Paris