G2Cdb::Human Disease report

Disease id
D00000170
Name
Bipolar disorder
Nervous system disease
yes

Genes (8)

Gene Name/Description Mutations Found Literature Mutations Type Genetic association?
G00001807 MBP
myelin basic protein
Y (8723042) Translocation (T) N
G00002098 GRIN1
glutamate receptor, ionotropic, N-methyl D-aspartate 1
Y (12610658) Single nucleotide polymorphism (SNP) Y
G00002098 GRIN1
glutamate receptor, ionotropic, N-methyl D-aspartate 1
Y (16969270) Single nucleotide polymorphism (SNP) N
G00002098 GRIN1
glutamate receptor, ionotropic, N-methyl D-aspartate 1
Y (16969270) Microsatellite polymorphism (MSP) N
G00001821 SHANK2
SH3 and multiple ankyrin repeat domains 2
N (15118355) Repeat polymorphism (RP) N
G00001821 SHANK2
SH3 and multiple ankyrin repeat domains 2
N (12895207) Repeat polymorphism (RP) N
G00002208 AKAP5
A kinase (PRKA) anchor protein 5
Y (16434481) Copy Number Polymorphism (CNP) Y
G00001420 GSK3B
glycogen synthase kinase 3 beta
Y (16289783) Polymorphism (P) N
G00001420 GSK3B
glycogen synthase kinase 3 beta
Y (16528748) Single nucleotide polymorphism (SNP) N
G00001420 GSK3B
glycogen synthase kinase 3 beta
Y (17357145) Copy Number Polymorphism (CNP) Y
G00000030 NOS1
nitric oxide synthase 1 (neuronal)
Y (14681919) Single nucleotide polymorphism (SNP) N
G00000027 GRIN2B
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
Y (16549338) Polymorphism (P) Y
G00001324 ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
Y (9646882) Dinucleotide polymorphism (DNP) Y

References

Literature (12)

Pubmed - human_disease

Pubmed - other

© G2C 2014. The Genes to Cognition Programme received funding from The Wellcome Trust and the EU FP7 Framework Programmes:
EUROSPIN (FP7-HEALTH-241498), SynSys (FP7-HEALTH-242167) and GENCODYS (FP7-HEALTH-241995).

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