G2Cdb::Literature Report

Confirmed rare copy number variants implicate novel genes in schizophrenia.
Tam GW, van de Lagemaat LN, Redon R, Strathdee KE, Croning MD, Malloy MP, Muir WJ, Pickard BS, Deary IJ, Blackwood DH, Carter NP, Grant SG
Biochem Soc Trans. 2010;38;445-51. PMID: 20298200 DOI: 10.1042/BST0380445
Automated design of genomic Southern blot probes.
Croning MD, Fricker DG, Komiyama NH, Grant SG
BMC Genomics. 2010;11;74. PMID: 20113467 DOI: 10.1186/1471-2164-11-74
Neuroproteomics: understanding the molecular organization and complexity of the brain.
Bayés A, Grant SG
Nat Rev Neurosci. 2009;10;635-46. PMID: 19693028 DOI: 10.1038/nrn2701
The origin and evolution of synapses.
Ryan TJ, Grant SG
Nat Rev Neurosci. 2009;10;701-12. PMID: 19738623 DOI: 10.1038/nrn2717
Reciprocal regulation of microRNA and mRNA profiles in neuronal development and synapse formation.
Manakov SA, Grant SG, Enright AJ
BMC Genomics. 2009;10;419. PMID: 19737397 DOI: 10.1186/1471-2164-10-419
A General Basis for Cognition in the Evolution of Synapse Signaling Complexes.
Grant SG
Cold Spring Harb Symp Quant Biol. 2009;. PMID: 19955255 DOI: 10.1101/sqb.2009.74.033
PSD-95 is essential for hallucinogen and atypical antipsychotic drug actions at serotonin receptors.
Abbas AI, Yadav PN, Yao WD, Arbuckle MI, Grant SG, Caron MG, Roth BL
J Neurosci. 2009;29;7124-36. PMID: 19494135 DOI: 10.1523/JNEUROSCI.1090-09.2009
Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins.
Fernández E, Collins MO, Uren RT, Kopanitsa MV, Komiyama NH, Croning MD, Zografos L, Armstrong JD, Choudhary JS, Grant SG
Mol Syst Biol. 2009;5;269. PMID: 19455133 DOI: 10.1038/msb.2009.27
The role of DNA copy number variation in schizophrenia.
Tam GW, Redon R, Carter NP, Grant SG
Biol Psychiatry. 2009;66;1005-12. PMID: 19748074 DOI: 10.1016/j.biopsych.2009.07.027
Neurotransmitters drive combinatorial multistate postsynaptic density networks.
Coba MP, Pocklington AJ, Collins MO, Kopanitsa MV, Uren RT, Swamy S, Croning MD, Choudhary JS, Grant SG
Sci Signal. 2009;2;ra19. PMID: 19401593 DOI: 10.1126/scisignal.2000102
PSD-95 uncouples dopamine-glutamate interaction in the D1/PSD-95/NMDA receptor complex.
Zhang J, Xu TX, Hallett PJ, Watanabe M, Grant SG, Isacson O, Yao WD
J Neurosci. 2009;29;2948-60. PMID: 19261890 DOI: 10.1523/JNEUROSCI.4424-08.2009
Integrin-mediated axoglial interactions initiate myelination in the central nervous system.
Câmara J, Wang Z, Nunes-Fonseca C, Friedman HC, Grove M, Sherman DL, Komiyama NH, Grant SG, Brophy PJ, Peterson A, ffrench-Constant C
J Cell Biol. 2009;185;699-712. PMID: 19451276 DOI: 10.1083/jcb.200807010
Evolution of NMDA receptor cytoplasmic interaction domains: implications for organisation of synaptic signalling complexes.
Ryan TJ, Emes RD, Grant SG, Komiyama NH
BMC Neurosci. 2008;9;6. PMID: 18197970 DOI: 10.1186/1471-2202-9-6
Kinase networks integrate profiles of N-methyl-D-aspartate receptor-mediated gene expression in hippocampus.
Coba MP, Valor LM, Kopanitsa MV, Afinowi NO, Grant SG
J Biol Chem. 2008;283;34101-7. PMID: 18815127 DOI: 10.1074/jbc.M804951200
G2Cdb: the Genes to Cognition database.
Croning MD, Marshall MC, McLaren P, Armstrong JD, Grant SG
Nucleic Acids Res. 2009;37;D846-51. PMID: 18984621 DOI: 10.1093/nar/gkn700
alpha-Isoform of calcium-calmodulin-dependent protein kinase II and postsynaptic density protein 95 differentially regulate synaptic expression of NR2A- and NR2B-containing N-methyl-d-aspartate receptors in hippocampus.
Park CS, Elgersma Y, Grant SG, Morrison JH
Neuroscience. 2008;151;43-55. PMID: 18082335 DOI: 10.1016/j.neuroscience.2007.09.075
Expression of AMPA receptor subunits at synapses in laminae I-III of the rodent spinal dorsal horn.
Polgár E, Watanabe M, Hartmann B, Grant SG, Todd AJ
Mol Pain. 2008;4;5. PMID: 18215271 DOI: 10.1186/1744-8069-4-5
Phosphoproteomic analysis of the mouse brain cytosol reveals a predominance of protein phosphorylation in regions of intrinsic sequence disorder.
Collins MO, Yu L, Campuzano I, Grant SG, Choudhary JS
Mol Cell Proteomics. 2008;7;1331-48. PMID: 18388127 DOI: 10.1074/mcp.M700564-MCP200
Opposing effects of PSD-93 and PSD-95 on long-term potentiation and spike timing-dependent plasticity.
Carlisle HJ, Fink AE, Grant SG, O'Dell TJ
J Physiol. 2008;586;5885-900. PMID: 18936077 DOI: 10.1113/jphysiol.2008.163469
Evolutionary expansion and anatomical specialization of synapse proteome complexity.
Emes RD, Pocklington AJ, Anderson CN, Bayes A, Collins MO, Vickers CA, Croning MD, Malik BR, Choudhary JS, Armstrong JD, Grant SG
Nat Neurosci. 2008;11;799-806. PMID: 18536710 DOI: 10.1038/nn.2135
NMDA receptor activation dephosphorylates AMPA receptor glutamate receptor 1 subunits at threonine 840.
Delgado JY, Coba M, Anderson CN, Thompson KR, Gray EE, Heusner CL, Martin KC, Grant SG, O'Dell TJ
J Neurosci. 2007;27;13210-21. PMID: 18045915 DOI: 10.1523/JNEUROSCI.3056-07.2007
Clustered gene expression changes flank targeted gene Loci in knockout mice.
Valor LM, Grant SG
PLoS ONE. 2007;2;e1303. PMID: 18074027 DOI: 10.1371/journal.pone.0001303
Toward a molecular catalogue of synapses.
Grant SG
Brain Res Rev. 2007;. PMID: 17572504 DOI: 10.1016/j.brainresrev.2007.05.003
Inhibition of the dopamine D1 receptor signaling by PSD-95.
Zhang J, Vinuela A, Neely MH, Hallett PJ, Grant SG, Miller GM, Isacson O, Caron MG, Yao WD
J Biol Chem. 2007;. PMID: 17369255 DOI: 10.1074/jbc.M611485200
Network activity-independent coordinated gene expression program for synapse assembly.
Valor LM, Charlesworth P, Humphreys L, Anderson CN, Grant SG
Proc Natl Acad Sci U S A. 2007;104;4658-63. PMID: 17360580 DOI: 10.1073/pnas.0609071104
The role of neuronal complexes in human X-linked brain diseases.
Laumonnier F, Cuthbert PC, Grant SG
Am J Hum Genet. 2007;80;205-20. PMID: 17236127 DOI: 10.1086/511441
Synaptic Ras GTPase activating protein regulates pattern formation in the trigeminal system of mice.
Barnett MW, Watson RF, Vitalis T, Porter K, Komiyama NH, Stoney PN, Gillingwater TH, Grant SG, Kind PC
J Neurosci. 2006;26;1355-65. PMID: 16452659
Expression of Transgenes Targeted to the Gt(ROSA)26Sor Locus Is Orientation Dependent.
Strathdee D, Ibbotson H, Grant SG
PLoS ONE. 2006;1;e4. PMID: 17183668 DOI: 10.1371/journal.pone.0000004
Integrating Synapse Proteomics with Transcriptional Regulation.
Valor LM, Grant SG
Behav Genet. 2006;. PMID: 16977502
Recording long-term potentiation of synaptic transmission by three-dimensional multi-electrode arrays.
Kopanitsa MV, Afinowi NO, Grant SG
BMC Neurosci. 2006;7;61. PMID: 16942609
High throughput protein expression screening in the nervous system - needs and limitations.
Anderson CN, Grant SG
J Physiol. 2006;. PMID: 16793899
Organization of brain complexity--synapse proteome form and function.
Pocklington AJ, Armstrong JD, Grant SG
Brief Funct Genomic Proteomic. 2006;5;66-73. PMID: 16769682
The proteomes of neurotransmitter receptor complexes form modular networks with distributed functionality underlying plasticity and behaviour.
Pocklington AJ, Cumiskey M, Armstrong JD, Grant SG
Mol Syst Biol. 2006;2;2006.0023. PMID: 16738568
Molecular characterization and comparison of the components and multiprotein complexes in the postsynaptic proteome.
Collins MO, Husi H, Yu L, Brandon JM, Anderson CN, Blackstock WP, Choudhary JS, Grant SG
J Neurochem. 2006;97 Suppl 1;16-23. PMID: 16635246
A novel role for cyclic guanosine 3',5'monophosphate signaling in synaptic plasticity: a selective suppressor of protein kinase A-dependent forms of long-term potentiation.
Makhinson M, Opazo P, Carlisle HJ, Godsil B, Grant SG, O'Dell TJ
Neuroscience. 2006;140;415-31. PMID: 16549271
The synapse proteome and phosphoproteome: a new paradigm for synapse biology.
Grant SG
Biochem Soc Trans. 2006;34;59-63. PMID: 16417483
Reconstructing protein complexes: From proteomics to systems biology.
Armstrong JD, Pocklington AJ, Cumiskey MA, Grant SG
Proteomics. 2006;6;4724-4731. PMID: 16892485
Differential expression of two NMDA receptor interacting proteins, PSD-95 and SynGAP during mouse development.
Porter K, Komiyama NH, Vitalis T, Kind PC, Grant SG
Eur J Neurosci. 2005;21;351-62. PMID: 15673435
Robust enrichment of phosphorylated species in complex mixtures by sequential protein and peptide metal-affinity chromatography and analysis by tandem mass spectrometry.
Collins MO, Yu L, Husi H, Blackstock WP, Choudhary JS, Grant SG
Sci STKE. 2005;2005;pl6. PMID: 16118397
Synapse proteomics of multiprotein complexes: en route from genes to nervous system diseases.
Grant SG, Marshall MC, Page KL, Cumiskey MA, Armstrong JD
Hum Mol Genet. 2005;. PMID: 16150739
Dynamic distribution of endoplasmic reticulum in hippocampal neuron dendritic spines.
Toresson H, Grant SG
Eur J Neurosci. 2005;22;1793-8. PMID: 16197520
AMPA receptor trafficking and GluR1.
Grant SG
Science. 2005;310;234-5; author reply 234-5. PMID: 16224003
Molecular characterization and comparison of the components and multiprotein complexes in the postsynaptic proteome.
Collins MO, Husi H, Yu L, Brandon JM, Anderson CN, Blackstock WP, Choudhary JS, Grant SG
J Neurochem. 2005;. PMID: 16236029
Proteomics in postgenomic neuroscience: the end of the beginning.
Choudhary J, Grant SG
Nat Neurosci. 2004;7;440-5. PMID: 15114355
The HUPO PSI's molecular interaction format--a community standard for the representation of protein interaction data.
Hermjakob H, Montecchi-Palazzi L, Bader G, Wojcik J, Salwinski L, Ceol A, Moore S, Orchard S, Sarkans U, von Mering C, Roechert B, Poux S, Jung E, Mersch H, Kersey P, Lappe M, Li Y, Zeng R, Rana D, Nikolski M, Husi H, Brun C, Shanker K, Grant SG, Sander C, Bork P, Zhu W, Pandey A, Brazma A, Jacq B, Vidal M, Sherman D, Legrain P, Cesareni G, Xenarios I, Eisenberg D, Steipe B, Hogue C, Apweiler R
Nat Biotechnol. 2004;22;177-83. PMID: 14755292 DOI: 10.1038/nbt926
Separable features of visual cortical plasticity revealed by N-methyl-D-aspartate receptor 2A signaling.
Fagiolini M, Katagiri H, Miyamoto H, Mori H, Grant SG, Mishina M, Hensch TK
Proc Natl Acad Sci U S A. 2003;100;2854-9. PMID: 12591944
PDZ domain proteins: plug and play!
Nourry C, Grant SG, Borg JP
Sci STKE. 2003;2003;RE7. PMID: 12709532 DOI: 10.1126/stke.2003.179.re7
Phosphatidylinositol 3-kinase regulates the induction of long-term potentiation through extracellular signal-related kinase-independent mechanisms.
Opazo P, Watabe AM, Grant SG, O'Dell TJ
J Neurosci. 2003;23;3679-88. PMID: 12736339
Systems biology in neuroscience: bridging genes to cognition.
Grant SG
Curr Opin Neurobiol. 2003;13;577-82. PMID: 14630221
Synapse signalling complexes and networks: machines underlying cognition.
Grant SG
Bioessays. 2003;25;1229-35. PMID: 14635258
SynGAP regulates ERK/MAPK signaling, synaptic plasticity, and learning in the complex with postsynaptic density 95 and NMDA receptor.
Komiyama NH, Watabe AM, Carlisle HJ, Porter K, Charlesworth P, Monti J, Strathdee DJ, O'Carroll CM, Martin SJ, Morris RG, O'Dell TJ, Grant SG
J Neurosci. 2002;22;9721-32. PMID: 12427827
Putting tubby on the MAP.
Grant SG
Nat Genet. 2002;30;347-8. PMID: 11925554 DOI: 10.1038/ng0402-347
Proteomics of multiprotein complexes: answering fundamental questions in neuroscience.
Grant SG, Husi H
Trends Biotechnol. 2001;19;S49-54. PMID: 11780971
Proteomics in neuroscience: from protein to network.
Grant SG, Blackstock WP
J Neurosci. 2001;21;8315-8. PMID: 11606617
Multiprotein complex signaling and the plasticity problem.
Grant SG, O'Dell TJ
Curr Opin Neurobiol. 2001;11;363-8. PMID: 11399436
Proteomics of the nervous system.
Husi H, Grant SG
Trends Neurosci. 2001;24;259-66. PMID: 11311377
Isolation of 2000-kDa complexes of N-methyl-D-aspartate receptor and postsynaptic density 95 from mouse brain.
Husi H, Grant SG
J Neurochem. 2001;77;281-91. PMID: 11279284
Targeted Gene Disruption in the CNS to Study Learning and Behavior
Grant SGN
Methods. 1996;10;406-16. PMID: 8954852
Analysis of NMDA receptor mediated synaptic plasticity using gene targeting: roles of Fyn and FAK non-receptor tyrosine kinases.
Grant SG
J Physiol Paris. 1996;90;337-8. PMID: 9089508
Fyn tyrosine kinase is required for normal amygdala kindling.
Cain DP, Grant SG, Saucier D, Hargreaves EL, Kandel ER
Epilepsy Res. 1995;22;107-14. PMID: 8777897
Targeting learning.
Grant SG, Silva AJ
Trends Neurosci. 1994;17;71-5. PMID: 7512771
Gene targeting and synaptic plasticity.
Grant SG
Curr Opin Neurobiol. 1994;4;687-92. PMID: 7849524
Analysis of somatic cell mutations at the glycophorin A locus in atomic bomb survivors: a comparative study of assay methods.
Langlois RG, Akiyama M, Kusunoki Y, DuPont BR, Moore DH, Bigbee WL, Grant SG, Jensen RH
Radiat Res. 1993;136;111-7. PMID: 8210326
Proto-oncogenes and signaling processes in neural tissues.
Sudol M, Grant SG, Maisonpierre PC
Neurochem Int. 1993;22;369-84. PMID: 8457773
Activation of cAMP-responsive genes by stimuli that produce long-term facilitation in Aplysia sensory neurons.
Kaang BK, Kandel ER, Grant SG
Neuron. 1993;10;427-35. PMID: 8384857
The mas proto-oncogene is developmentally regulated in the rat central nervous system.
Martin KA, Grant SG, Hockfield S
Brain Res Dev Brain Res. 1992;68;75-82. PMID: 1521325
Pharmacological and genetic approaches to the analysis of tyrosine kinase function in long-term potentiation.
O'Dell TJ, Grant SG, Karl K, Soriano PM, Kandel ER
Cold Spring Harb Symp Quant Biol. 1992;57;517-26. PMID: 1339688
Overexpression of an Aplysia shaker K+ channel gene modifies the electrical properties and synaptic efficacy of identified Aplysia neurons.
Kaang BK, Pfaffinger PJ, Grant SG, Kandel ER, Furukawa Y
Proc Natl Acad Sci U S A. 1992;89;1133-7. PMID: 1310540
Somatic cell genotoxicity at the glycophorin A locus in humans.
Jensen RH, Grant SG, Langlois RG, Bigbee WL
Prog Clin Biol Res. 1991;372;329-39. PMID: 1956927
Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors.
O'Dell TJ, Kandel ER, Grant SG
Nature. 1991;353;558-60. PMID: 1656271 DOI: 10.1038/353558a0
Long-term facilitation in Aplysia: persistent phosphorylation and structural changes.
Schacher S, Glanzman D, Barzilai A, Dash P, Grant SG, Keller F, Mayford M, Kandel ER
Cold Spring Harb Symp Quant Biol. 1990;55;187-202. PMID: 1966763
Localization of the mouse Mcf-2 (Dbl) protooncogene within a conserved linkage group on the mouse X chromosome.
Grant SG, Mattei MG, Galland F, Stephenson DA, Keitz BT, Birnbaum D, Chapman VM
Cytogenet Cell Genet. 1990;54;175-81. PMID: 2265564
cis-acting determinants of basal and lipid-regulated apolipoprotein A-IV expression in mice.
Williams SC, Grant SG, Reue K, Carrasquillo B, Lusis AJ, Kinniburgh AJ
J Biol Chem. 1989;264;19009-16. PMID: 2808406