G2Cdb::Gene Report


Gene id G00001242
Gene name Akr1a4 (MGI)
Species Mus musculus
Description aldo-keto reductase family 1, member A4 (aldehyde reductase)
Databases

Marker Symbol
MGI:1929955 (MGI)

Curated Gene
OTTMUSG00000009532 (Vega mouse gene)

Gene
717 (G2Cdb plasticity & disease)
58810 (Entrez Gene)
ENSMUSG00000028692 (Ensembl mouse gene)

Gene Expression
NM_021473 (Allen Brain Atlas)
58810 (Genepaint)

Literature
103830 (OMIM)

Protein Sequence
Q9JII6 (UniProt)
Literature
(9 items)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004;14;2121-7. PMID: 15489334 DOI: 10.1101/gr.2596504

Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas.
Watahiki A, Waki K, Hayatsu N, Shiraki T, Kondo S, Nakamura M, Sasaki D, Arakawa T, Kawai J, Harbers M, Hayashizaki Y, Carninci P
Nat Methods. 2004;1;233-9. PMID: 15782199 DOI: 10.1038/nmeth719

A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Hansen J, Floss T, Van Sloun P, Füchtbauer EM, Vauti F, Arnold HH, Schnütgen F, Wurst W, von Melchner H, Ruiz P
Proc Natl Acad Sci U S A. 2003;100;9918-22. PMID: 12904583

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic Acids Res. 2003;31;278-81. PMID: 12520002

Cloning and developmental expression of mouse aldehyde reductase (AKR1A4).
Allan D, Lohnes D
Mech Dev. 2000;94;271-5. PMID: 10842086

Regulation of aldehyde reductase expression by STAF and CHOP.
Barski OA, Papusha VZ, Kunkel GR, Gabbay KH
Genomics. 2004;83;119-29. PMID: 14667815

Developmental expression and function of aldehyde reductase in proximal tubules of the kidney.
Barski OA, Papusha VZ, Ivanova MM, Rudman DM, Finegold MJ
Am J Physiol Renal Physiol. 2005;289;F200-7. PMID: 15769935 DOI: 10.1152/ajprenal.00411.2004

Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Zambrowicz BP, Abuin A, Ramirez-Solis R, Richter LJ, Piggott J, BeltrandelRio H, Buxton EC, Edwards J, Finch RA, Friddle CJ, Gupta A, Hansen G, Hu Y, Huang W, Jaing C, Key BW, Kipp P, Kohlhauff B, Ma ZQ, Markesich D, Payne R, Potter DG, Qian N, Shaw J, Schrick J, Shi ZZ, Sparks MJ, Van Sligtenhorst I, Vogel P, Walke W, Xu N, Zhu Q, Person C, Sands AT
Proc Natl Acad Sci U S A. 2003;100;14109-14. PMID: 14610273

Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray.
Tanaka TS, Jaradat SA, Lim MK, Kargul GJ, Wang X, Grahovac MJ, Pantano S, Sano Y, Piao Y, Nagaraja R, Doi H, Wood WH, Becker KG, Ko MS
Proc Natl Acad Sci U S A. 2000;97;9127-32. PMID: 10922068

Homology
Orthologues
G00002491 (Homo sapiens)
Gene lists Mouse PSD
Mouse clathrin
Mouse Synaptosome
Mouse PSP