G2Cdb::Human Disease Report


Disease id D00000068
Name Astrocytoma (anaplastic)
Nervous system disease Yes
Genes
G00001624 (PIK3CA) phosphoinositide-3-kinase
G00000036 (NF1) neurofibromin 1 (neurofib
Literature
(2 items)
Somatic mutations in the neurofibromatosis 1 gene in human tumors.
Li Y, Bollag G, Clark R, Stevens J, Conroy L, Fults D, Ward K, Friedman E, Samowitz W, Robertson M
Cell. 1992;69;275-81. PMID: 1568247

Mutations of PIK3CA in anaplastic oligodendrogliomas, high-grade astrocytomas, and medulloblastomas.
Broderick DK, Di C, Parrett TJ, Samuels YR, Cummins JM, McLendon RE, Fults DW, Velculescu VE, Bigner DD, Yan H
Cancer Res. 2004;64;5048-50. PMID: 15289301