G2C::Proteomics

Targeted tandem affinity purification of PSD-95 recovers core
postsynaptic complexes and schizophrenia susceptibility proteins
Esperanza Fernandez, Mark O Collins, Rachel T Uren, Maksym V Kopanitsa, Noboru H Komiyama,
Mike DR Croning, Lysimachos Zografos, J Douglas Armstrong, Jyoti S Choudhary and Seth GN Grant


Supplementary Table 5. Comparison to proteins found in receptor complexes and synaptic lists.

Numbers of common proteins found in the MASC/NRC, AMPA receptor (AMPA), metabotrobic glutamate
receptor 5 (mGluR5)
, PSD and PSP lists (Collins et al., 2006) and PSD-95 immunoprecipitation list (Dosemeci et al., 2007) with all the proteins indentified in this study (301 proteins, Supplementary Table 1) and in the PSD-95 core complexes (118 proteins).

Synaptic ComplexPSD-95 ComplexPSD-95 Core Complex
MASC/NRC6948
AMPA receptor77
mGLUR5179
PSD18389
PSP18890
Dosemeci et al.7949
Total Proteins301118